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- 5 MeO DMT DOSAGE -
"5-MeO-DMT is a short acting tryptamine very similar in nature to DMT. It is often found as very small white crystals (like salt) and is generally smoked and less commonly insufflated. Dosages are very sensitive. People react very differently to different doses, and insufficient measuring instruments add to the risk. Some individuals have world-shattering effects with less than 5 mg." EROWID
5-MeO-DMT DOSAGE REPORTS:
Smoked- Threshold 1-2 mg, Light 2-5 mg, Common 5-10 mg, Strong 10-20 mg
Onset : 0-30sec, Peak : 1-15mins, Duration : 30mins, After Effects : 1hr
Snuffed: Threshold 3-5 mg, Light 5-10 mg, Common 8-15 mg, Strong 10-25 mg
Onset : 5mins, Peak : 10-30mins, Duration : 30-45mins, After Effects : 1-3hrs
Oral: Threshold ?? mg, Light ?? mg, Common 20-30 mg, Strong 30+ mg
Note: Dosages are based on Jonathan Ott's presentation at the San Francisco Ayahuasca Conference 2000.
Sublingual: Threshold ?? mg, Light 10 mg, Common ?? mg, Strong ?? mg
Note: Dosages are based on Jonathan Ott's presentation at the San Francisco Ayahuasca Conference 2000.
(Sonoran Desert Toad venom on glass)
The information listed here has been made available from the EROWID website.
The research to date tells us conclusively that 5-MeO-DMT and bufotenine are the psychoactive compounds present in the venom of B. alvarius. Most people assume that 5-15% of the dried material is 5-MeO-DMT and that 3% is bufotenine, although, this is actually inconclusive. The actual levels of 5-MeO-DMT and bufotenine contained in the venom itself may be somewhat higher than this, however, the variability in the quantity of these compounds present in any single toad's venom may render this conclusion irrelevant in practicality. One may never be completely certain how much of the active compounds are actually present in any given dose.
That's one basic problem with all natural sources of drugs: the potency varies greatly. This is even more of an issue for 5-MeO-DMT, since the dose is an important variable. One possible solution to increase the uniformity of the dose is to aggregate the total season's harvest and finely and thoroughly mix it together into a uniform consistency by crushing the venom into a fine powder using a mortar and pestle, or some similar device.
Store the venom frozen in a container that blocks out light, such as a film canister for long-term storage. Condensation usually occurs when you take the container out of the freezer, so leave it sealed until it warms up.
So what's a proper dose of toad venom?
If we assume that an average of at least 10% of the venom is 5-MeO-DMT:
Smoked Toad Venom Dosages:
Threshold 10-20 mg
Light 20-50 mg
Common 50-100 mg
Strong 100-200 mg
However, if we assume that an average of at least 25% of the venom is 5-MeO-DMT:
Smoked Toad Venom Dosages:
Threshold 4-8 mg
Light 8-20 mg
Common 20-40 mg
Strong 40-80 mg
Please keep in mind that 5-MeO-DMT is not the only active material present in the toad venom!
Toad venom contains, quite possibly, the strongest psychoactive substance on the planet: 5-MeO-DMT. There are two people who did high doses (of 5-MeO-DMT) and had severe anxiety problems (could not sleep for a week); one is still having anxiety problems a few years later. Usually, it's recommend that people start with a low dose. But so many people try 5-MeO-DMT once and just can not find the courage to do it again, yet at the same time, they will say it was a very significant life experience for them. So, possibly a "full" dose of perhaps 10-12 mg 5-MeO-DMT makes sense. This would be equivalent, in toad venom, to 40-48mg (assuming 25%) or 100-120mg (assuming 10%). Anyone with a kind of fragile grip on reality, or who has problems with anxiety, should probably not do it.
One very good suggestion is to start with a "light" dose. Assuming that the highest possible concentration of 5-MeO-DMT in the venom is 25%, then 16 mg of venom might be a good starting dose.
The practical problem is the larger doses can be so overwhelming that many people just don't have the courage (and/or are too traumatized) to try again. But an under-dose, though perhaps disappointing, gives one more confidence to try the next level. Also, starting with a lower dose is not very "expensive" in terms of material used; here it's only 16 mg.
Then as far as increasing doses, the rule of thumb heard most is:
- from a dose that does little or nothing: increase 100%
- from a dose that has significant effects: increase 50%
There is a drug-use phenomenon that is often referred to by the popular title of "toad-licking." The toad involved is the Sonoran Desert Toad, also called the Colorado River Toad, and carries the binomial Bufo alvarius. It is not the closely related marine toad Bufo marinus, as some people have insisted, prompted by the early Olmec and Mayan iconography. Of course the licking myth is newspaper hype -- it is the venom that is active, and it is smoked. When the desert toad is stroked near the parotid glands in the neck region, there is the squirting out of this venom and when it is allowed to dry on a hard surface it takes on the texture of rubber cement. It contains up to 15% 5-MeO-DMT, as well as N-methyl-5-methoxytryptamine, 5-MeO-NMT and Bufotenine, which have their own entries.
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